HEXA Antibody
Product Specifications
Background
HEXA is the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases.
NCBI Gene ID
3073
Swiss Prot
P06865
Accession Number
P06865
Host
Rabbit
Reactivity
Human
Immunogen
This HEXA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-343 amino acids from the Central region of human HEXA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
61 kDa
Fragment
Rabbit Ig
Symbol
HEXA
NCBI Official Name
Beta-hexosaminidase subunit alpha
NCBI Organism
Homo sapiens
Background Reference 01
Park, N.J., et.al., Pediatr. Res. (2009)
Background Reference 02
Pennybacker, M., et.al., J. Biol. Chem. 271 (29), 17377-17382 (1996)
Other Product Names
Beta-hexosaminidase subunit alpha, Beta-N-acetylhexosaminidase subunit alpha, Hexosaminidase subunit A, N-acetyl-beta-glucosaminidase subunit alpha, HEXA
Tested Applications
WB, IHC-P, Flow
Protein ID
311033393
Physical Properties
Liquid
Frequently Asked Questions
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