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IGFBP4 Antibody

Product Specifications

Background

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.

NCBI Gene ID

3487

Swiss Prot

P22692

Accession Number

P22692

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This IGFBP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-124 amino acids from the Central region of human IGFBP4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Pig

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Symbol

IGFBP4

NCBI Official Name

Insulin-like growth factor-binding protein 4

NCBI Organism

Homo sapiens

Background Reference 01

Giroux, S., et al. Bone 47 (5) :975-981 (2010)

Background Reference 02

Canzian, F., et al. Hum. Mol. Genet. 19 (19) :3873-3884 (2010)

Background Reference 03

Bartling, B., et al. Int. J. Mol. Med. 25 (1) :89-96 (2010)

Background Reference 04

Johnatty, S.E., et al. PLoS Genet. (7), E1001016 (2010) :

Other Product Names

Insulin-like growth factor-binding protein 4, IBP-4, IGF-binding protein 4, IGFBP-4, IGFBP4, IBP4

Tested Applications

WB, IHC-P

Protein ID

124065

Physical Properties

Liquid

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