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OGG1 Antibody

Product Specifications

Background

OGG1 is the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage.

NCBI Gene ID

4968

Swiss Prot

O15527

Accession Number

O15527

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This OGG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-345 amino acids from the C-terminal region of human OGG1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

OGG1

NCBI Official Name

N-glycosylase/DNA lyase

NCBI Organism

Homo sapiens

Background Reference 01

Wozniak, K., et.al., J. Biomed. Biotechnol. 2009, 827562 (2009)

Other Product Names

N-glycosylase/DNA lyase, 8-oxoguanine DNA glycosylase, 322-, DNA- (apurinic or apyrimidinic site) lyase, AP lyase, OGG1, MMH, MUTM, OGH1

Tested Applications

WB

Physical Properties

Liquid

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