OGG1 Antibody
Product Specifications
Background
OGG1 is the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage.
NCBI Gene ID
4968
Swiss Prot
O15527
Accession Number
O15527
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This OGG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-345 amino acids from the C-terminal region of human OGG1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
OGG1
NCBI Official Name
N-glycosylase/DNA lyase
NCBI Organism
Homo sapiens
Background Reference 01
Wozniak, K., et.al., J. Biomed. Biotechnol. 2009, 827562 (2009)
Other Product Names
N-glycosylase/DNA lyase, 8-oxoguanine DNA glycosylase, 322-, DNA- (apurinic or apyrimidinic site) lyase, AP lyase, OGG1, MMH, MUTM, OGH1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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