TPH1 Antibody
Product Specifications
Background
TPH1 is a member of the aromatic amino acid hydroxylase family. This protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter.
NCBI Gene ID
7166
Swiss Prot
P17752
Accession Number
P17752
Host
Rabbit
Reactivity
Human
Immunogen
This TPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-62 amino acids from the N-terminal region of human TPH1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Chicken, Rabbit, Rat, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Symbol
TPH1
NCBI Official Name
Tryptophan 5-hydroxylase 1
NCBI Organism
Homo sapiens
Background Reference 01
Johansson, T.A., et.al., BMC Cancer 9, 321 (2009)
Background Reference 02
Kuhn, D.M., et.al., J. Neurochem. 68 (5), 2220-2223 (1997)
Other Product Names
Tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1, TPH1, TPH, TPRH, TRPH
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
116242823
Physical Properties
Liquid
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