OTC Antibody
Product Specifications
Background
OTC is a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia.
NCBI Gene ID
5009
Swiss Prot
P00480
Accession Number
P00480
Host
Rabbit
Reactivity
Human
Immunogen
This OTC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-98 amino acids from the Central region of human OTC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
40 kDa
Fragment
Rabbit Ig
Symbol
OTC
NCBI Official Name
Ornithine carbamoyltransferase, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Hansmannel, F., et.al., Neurosci. Lett. 449 (1), 76-80 (2009)
Other Product Names
Ornithine carbamoyltransferase, mitochondrial, Ornithine transcarbamylase, OTCase, OTC
Tested Applications
WB, IHC-P, Flow
Protein ID
84028235
Physical Properties
Liquid
Frequently Asked Questions
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