FMO3 Antibody

Product Specifications

Background

FMO3 is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. It N-oxygenates primary aliphatic alkylamines as well as secondary and tertiary amines. It plays an important role in the metabolism of trimethylamine (TMA), via the production of TMA N-oxide (TMAO) . Is also able to perform S-oxidation when acting on sulfide compounds.

NCBI Gene ID

2328

Swiss Prot

P31513

Accession Number

P31513

Host

Rabbit

Reactivity

Human

Immunogen

This FMO3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-56 amino acids from the N-terminal region of human FMO3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

60 kDa

Fragment

Rabbit Ig

Symbol

FMO3

NCBI Official Name

Dimethylaniline monooxygenase [N-oxide-forming] 3

NCBI Organism

Homo sapiens

Background Reference 01

Allerston, C.K., et.al., Mol. Genet. Metab. 98 (1-2), 198-202 (2009)

Other Product Names

Dimethylaniline monooxygenase [N-oxide-forming] 3, Dimethylaniline oxidase 3, FMO II, FMO form 2, Hepatic flavin-containing monooxygenase 3, FMO 3, Trimethylamine monooxygenase, FMO3