SPINK5 Antibody

Product Specifications

Background

SPINK5 is a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The inhibitor may play a role in skin and hair morphogenesis and anti-inflammatory and/or antimicrobial protection of mucous epithelia. Mutations may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy.

NCBI Gene ID

11005

Swiss Prot

Q9NQ38

Accession Number

Q9NQ38

Host

Rabbit

Reactivity

Human

Immunogen

This SPINK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-217 amino acids from the N-terminal region of human SPINK5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

121 kDa

Fragment

Rabbit Ig

Symbol

SPINK5

NCBI Official Name

Serine protease inhibitor Kazal-type 5

NCBI Organism

Homo sapiens

Background Reference 01

Nin, M., et.al., J. Dermatol. Sci. 54 (1), 17-24 (2009)

Other Product Names

Serine protease inhibitor Kazal-type 5, Lympho-epithelial Kazal-type-related inhibitor, LEKTI, Hemofiltrate peptide HF6478, Hemofiltrate peptide HF7665, SPINK5