GNAS Antibody
Product Specifications
Background
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G (s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms.
NCBI Gene ID
2778
Swiss Prot
Q5JWF2
Accession Number
Q5JWF2
Host
Rabbit
Reactivity
Human
Immunogen
This GNAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 640-667 amino acids from the Central region of human GNAS.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=62-509
Calculated Molecular Weight
111 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:4000
Symbol
GNAS
NCBI Official Name
Guanine nucleotide-binding protein G (s) subunit alpha isoforms XLas
NCBI Organism
Homo sapiens
Background Reference 01
Liu, C., et.al., Eur Arch Otorhinolaryngol (2009)
Background Reference 02
Nishihara, E., et.al., Endocr. J. 56 (6), 791-798 (2009)
Other Product Names
Guanine nucleotide-binding protein G (s) subunit alpha isoforms XLas, Adenylate cyclase-stimulating G alpha protein, Extra large alphas protein, XLalphas, GNAS, GNAS1 {ECO:0000303|PubMed:9707596}
Tested Applications
WB
Protein ID
116248089
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
