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BCKDHA Antibody

Product Specifications

Background

The branched-chain alpha-keto acid (BCAA) dehydrogenase (BCKD) complex is an innter mitochondrial enzyme complex that catalyzes the second major step in the catabolism of the branched-chain amino acids leucine, isoleucine, and valine. The BCKD complex consists of three catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3) . BCKDHA is the alpha subunit of the decarboxylase (E1) component.

NCBI Gene ID

593

Swiss Prot

P12694

Accession Number

P12694

Host

Rabbit

Reactivity

Human

Immunogen

This BCKDHA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 362-390 amino acids from the C-terminal region of human BCKDHA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=62-489

Calculated Molecular Weight

50 kDa

Fragment

Rabbit Ig

Symbol

BCKDHA

NCBI Official Name

2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Flaschker, N., et.al., J. Inherit. Metab. Dis. 30 (6), 903-909 (2007)

Other Product Names

2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial, Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain, BCKDE1A, BCKDH E1-alpha, BCKDHA

Tested Applications

WB, IHC-P, Flow

Physical Properties

Liquid

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