KYNU Antibody

Product Specifications

Background

KYNU is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. KYNU is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway.

NCBI Gene ID

8942

Swiss Prot

Q16719

Accession Number

Q16719

Host

Rabbit

Reactivity

Human

Immunogen

This KYNU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 359-386 amino acids from the C-terminal region of human KYNU.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

52 kDa

Fragment

Rabbit Ig

Symbol

KYNU

NCBI Official Name

Kynureninase {ECO:0000255|HAMAP-Rule:MF_03017}

NCBI Organism

Homo sapiens

Background Reference 01

Christensen, M., et.al., J. Inherit. Metab. Dis. 30 (2), 248-255 (2007)

Other Product Names

Kynureninase {ECO:0000255|HAMAP-Rule:MF_03017}, 3713 {ECO:0000255|HAMAP-Rule:MF_03017}, L-kynurenine hydrolase {ECO:0000255|HAMAP-Rule:MF_03017}, KYNU {ECO:0000255|HAMAP-Rule:MF_03017}