SPARC Antibody

Product Specifications

Background

Secreted protein acidic and rich in cysteine/osteonectin/BM40, or SPARC, is a matrix-associated protein that elicits changes in cell shape, inhibits cell-cycle progression, and influences the synthesis of extracellular matrix (ECM) .

NCBI Gene ID

6678

Swiss Prot

P09486

Accession Number

P09486

Host

Rabbit

Reactivity

Human

Immunogen

This SPARC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-251 amino acids from the C-terminal region of human SPARC.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Cell Cycle, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Pig, Rabbit, Rat, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Symbol

SPARC

NCBI Official Name

SPARC

NCBI Organism

Homo sapiens

Background Reference 01

Said, N., Oncogene 28 (39), 3487-3498 (2009)

Background Reference 02

Maloney, S.C., Anticancer Res. 29 (8), 3059-3064 (2009)

Other Product Names

SPARC, Basement-membrane protein 40, BM-40, Osteonectin, ON, Secreted protein acidic and rich in cysteine, SPARC, ON

Tested Applications

WB, IHC-P, Flow

Protein ID

129283

Physical Properties

Liquid

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