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AMT Antibody

Product Specifications

Background

The enzyme system for cleavage of glycine (glycine cleavage system; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase; MIM 238300), H protein (a lipoic acid-containing protein; MIM 238330), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase; MIM 238331) . Glycine encephalopathy (GCE; MIM 605899) may be due to a defect in any one of these enzymes.

NCBI Gene ID

275

Swiss Prot

P48728

Accession Number

P48728

Host

Rabbit

Reactivity

Human

Immunogen

This AMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human AMT.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

44 kDa

Fragment

Rabbit Ig

Symbol

AMT

NCBI Official Name

Aminomethyltransferase, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Nanao, K., Genomics 19 (1), 27-30 (1994)

Other Product Names

Aminomethyltransferase, mitochondrial, Glycine cleavage system T protein, GCVT, AMT, GCST

Tested Applications

WB, IHC-P, Flow

Protein ID

1346122

Physical Properties

Liquid

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