Lamin B2 Antibody
Product Specifications
Background
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Lamin B2 is one of the two B type proteins, B2.
NCBI Gene ID
84823
Swiss Prot
Q03252
Accession Number
Q03252
Host
Rabbit
Reactivity
Human
Immunogen
This Lamin B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-504 amino acids from the C-terminal region of human Lamin B2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
68 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
LMNB2
NCBI Official Name
Lamin-B2
NCBI Organism
Homo sapiens
Background Reference 01
Schumacher, J., FEBS Lett. 580 (26), 6211-6216 (2006)
Other Product Names
Lamin-B2, LMNB2, LMN2
Tested Applications
WB
Protein ID
23503078
Physical Properties
Liquid
Curated Selection
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