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DCD Antibody

Product Specifications

Background

DCD is a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients.

NCBI Gene ID

117159

Swiss Prot

P81605

Accession Number

P81605

Host

Rabbit

Reactivity

Human

Immunogen

This DCD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-103 amino acids from the C-terminal region of human DCD.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Obesity

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

11 kDa

Fragment

Rabbit Ig

Symbol

DCD

NCBI Official Name

Dermcidin

NCBI Organism

Homo sapiens

Background Reference 01

Todorov, P.T., J. Biol. Chem. 272 (19), 12279-12288 (1997)

Other Product Names

Dermcidin, 34--, Preproteolysin, Survival-promoting peptide, DCD-1, DCD, AIDD, DSEP

Tested Applications

WB, IHC-P, Flow

Protein ID

20141302

Physical Properties

Liquid

Frequently Asked Questions

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