DCD Antibody
Product Specifications
Background
DCD is a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients.
NCBI Gene ID
117159
Swiss Prot
P81605
Accession Number
P81605
Host
Rabbit
Reactivity
Human
Immunogen
This DCD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-103 amino acids from the C-terminal region of human DCD.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Obesity
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
11 kDa
Fragment
Rabbit Ig
Symbol
DCD
NCBI Official Name
Dermcidin
NCBI Organism
Homo sapiens
Background Reference 01
Todorov, P.T., J. Biol. Chem. 272 (19), 12279-12288 (1997)
Other Product Names
Dermcidin, 34--, Preproteolysin, Survival-promoting peptide, DCD-1, DCD, AIDD, DSEP
Tested Applications
WB, IHC-P, Flow
Protein ID
20141302
Physical Properties
Liquid
Curated Selection
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