SERPINC1 Antibody
Product Specifications
Background
SERPINC1 is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin.
NCBI Gene ID
462
Swiss Prot
P01008
Accession Number
P01008
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This SERPINC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-393 amino acids from the C-terminal region of human SERPINC1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
53 kDa
Fragment
Rabbit Ig
Symbol
SERPINC1
NCBI Official Name
Antithrombin-III
NCBI Organism
Homo sapiens
Background Reference 01
Doi, T., Arch. Biochem. Biophys. 489 (1-2), 62-67 (2009)
Background Reference 02
Sun, X.J., J. Biol. Chem. 264 (19), 11288-11293 (1989)
Other Product Names
Antithrombin-III, ATIII, Serpin C1, SERPINC1, AT3
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
113936
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items