OGT Antibody
Product Specifications
Background
O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains nine tetratricopeptide repeats and a putative bipartite nuclear localization signal.
NCBI Gene ID
8473
Swiss Prot
O15294
Accession Number
O15294
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This OGT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1017-1046 amino acids from the C-terminal region of human OGT.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Pig, Rabbit, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
117 kDa
Fragment
Rabbit Ig
Symbol
OGT
NCBI Official Name
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
NCBI Organism
Homo sapiens
Background Reference 01
Roeder, R.G., Nature 459 (7245), 455-459 (2009)
Background Reference 02
Taylor, R.P., J. Biol. Chem. 284 (6), 3425-3432 (2009)
Background Reference 03
Slawson, C., Mol. Biol. Cell 19 (10), 4130-4140 (2008)
Other Product Names
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, O-GlcNAc transferase subunit p110, O-linked N-acetylglucosamine transferase 110 kDa subunit, OGT, OGT
Tested Applications
WB, IHC-P
Physical Properties
Liquid
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