HOXA5 Antibody
Product Specifications
Background
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA5 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.
NCBI Gene ID
3202
Swiss Prot
P20719
Accession Number
P20719
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This HOXA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-223 amino acids from the C-terminal region of human HOXA5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Drosophila, Zebrafish, Chicken, Bovine, Rat, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
29 kDa
Fragment
Rabbit Ig
Symbol
HOXA5
NCBI Official Name
Homeobox protein Hox-A5
NCBI Organism
Homo sapiens
Background Reference 01
Chen, Y., Blood 111 (3), 1217-1226 (2008)
Background Reference 02
Chen, H., Cancer Res. 67 (17), 8007-8013 (2007)
Other Product Names
Homeobox protein Hox-A5, Homeobox protein Hox-1C, HOXA5, HOX1C
Tested Applications
WB, Flow
Protein ID
52788238
Physical Properties
Liquid
Curated Selection
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