ZWINT Antibody
Product Specifications
Background
ZWINT is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells.
NCBI Gene ID
11130
Swiss Prot
O95229
Accession Number
O95229
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This ZWINT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-88 amino acids from the Central region of human ZWINT.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=62-403
Calculated Molecular Weight
31 kDa
Fragment
Rabbit Ig
Symbol
ZWINT
NCBI Official Name
ZW10 interactor
NCBI Organism
Homo sapiens
Background Reference 01
Famulski, J.K., J. Cell Biol. 180 (3), 507-520 (2008) Kops, G.J., J. Cell Biol. 169 (1), 49-60 (2005) Wang, H., J. Biol. Chem. 279 (52), 54590-54598 (2004)
Other Product Names
ZW10 interactor, ZW10-interacting protein 1, Zwint-1, ZWINT
Tested Applications
WB, IHC-P, Flow
Physical Properties
Liquid
Curated Selection
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