XPO1 Antibody
Product Specifications
Background
XPO1 mediates leucine-rich nuclear export signal (NES) -dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
NCBI Gene ID
7514
Swiss Prot
O14980
Accession Number
O14980
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This XPO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 817-846 amino acids from the C-terminal region of human XPO1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
123 kDa
Fragment
Rabbit Ig
Symbol
XPO1
NCBI Official Name
Exportin-1
NCBI Organism
Homo sapiens
Background Reference 01
Shen, A., Neurosurgery 65 (1), 153-159 (2009)
Background Reference 02
Dong, X., Nat. Struct. Mol. Biol. 16 (5), 558-560 (2009)
Other Product Names
Exportin-1, Exp1, Chromosome region maintenance 1 protein homolog, XPO1, CRM1
Tested Applications
WB, IHC-P, Flow
Physical Properties
Liquid
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![S100B Mouse Monoclonal Antibody [Clone ID: SA-12]](https://cdn.genprice.uk/products/937/68dd189c061270361e8fc840/imageurl/am20665pu-n.webp)
AM20665PU-N 100 µg
S100B Mouse Monoclonal Antibody [Clone ID: SA-12]
Sign In for Pricing
View Details 
BNC741950-500 1x 500 µL
Bcl-6 (Follicular Lymphoma Marker) (rBCL6/1527), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details