TAGLN Antibody

Product Specifications

Background

TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear.

NCBI Gene ID

6876

Swiss Prot

Q01995

Accession Number

Q01995

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This TAGLN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-167 amino acids from the C-terminal region of human TAGLN.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

23 kDa

Fragment

Rabbit Ig

Symbol

TAGLN

NCBI Official Name

Transgelin

NCBI Organism

Homo sapiens

Background Reference 01

Zhao, L., Mod. Pathol. 22 (6), 786-796 (2009) Leguillette, R., Am. J. Respir. Crit. Care Med. 179 (3), 194-204 (2009) Yu, H., FASEB J. 22 (6), 1778-1789 (2008)