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SERPING1 Antibody

Product Specifications

Background

SERPING1 is a highly glycosylated plasma protein involved in the regulation of the complement cascade. This protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE) .

NCBI Gene ID

710

Swiss Prot

P05155

Accession Number

P05155

Host

Rabbit

Reactivity

Human

Immunogen

This SERPING1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-314 amino acids from the Central region of human SERPING1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

55 kDa

Fragment

Rabbit Ig

Symbol

SERPING1

NCBI Official Name

Plasma protease C1 inhibitor

NCBI Organism

Homo sapiens

Background Reference 01

Park, K.H., Mol. Vis. 15, 200-207 (2009)

Background Reference 02

Gosswein, T., Cytogenet. Genome Res. 121 (3-4), 181-188 (2008)

Other Product Names

Plasma protease C1 inhibitor, C1 Inh, C1Inh, C1 esterase inhibitor, C1-inhibiting factor, Serpin G1, SERPING1, C1IN, C1NH

Tested Applications

WB, IHC-P, IF

Protein ID

124096

Physical Properties

Liquid

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