PLZF Antibody

Product Specifications

Background

PLZF is a member of the Krueppel C2H2-type zinc-finger protein family and a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL) .

NCBI Gene ID

7704

Swiss Prot

Q05516

Accession Number

Q05516

Host

Rabbit

Reactivity

Human

Immunogen

This PLZF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 637-666 amino acids from the C-terminal region of human PLZF.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

74 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ZBTB16

NCBI Official Name

Zinc finger and BTB domain-containing protein 16

NCBI Organism

Homo sapiens

Background Reference 01

Shi, J., Int. J. Cancer 125 (7), 1558-1565 (2009)

Background Reference 02

Doulatov, S., Genes Dev. 23 (17), 2076-2087 (2009)

Other Product Names

Zinc finger and BTB domain-containing protein 16, Promyelocytic leukemia zinc finger protein, Zinc finger protein 145, Zinc finger protein PLZF, ZBTB16, PLZF, ZNF145