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CALD1 Antibody

Product Specifications

Background

CALD1 is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca (2+) -calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca (2+) -dependent inhibition of smooth muscle contraction.

NCBI Gene ID

800

Swiss Prot

Q05682

Accession Number

Q05682

Host

Rabbit

Reactivity

Human

Immunogen

This CALD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-457 amino acids from the Central region of human CALD1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

93 kDa

Fragment

Rabbit Ig

Symbol

CALD1

NCBI Official Name

Caldesmon

NCBI Organism

Homo sapiens

Background Reference 01

Yoshio, T., FEBS Lett. 581 (20), 3777-3782 (2007) Mani, R.S., Biochemistry 31 (47), 11896-11901 (1992)

Other Product Names

Caldesmon, CDM, CALD1, CAD, CDM

Tested Applications

WB, IHC-P, Flow

Protein ID

338817891

Physical Properties

Liquid

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