CALD1 Antibody
Product Specifications
Background
CALD1 is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca (2+) -calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca (2+) -dependent inhibition of smooth muscle contraction.
NCBI Gene ID
800
Swiss Prot
Q05682
Accession Number
Q05682
Host
Rabbit
Reactivity
Human
Immunogen
This CALD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-457 amino acids from the Central region of human CALD1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
93 kDa
Fragment
Rabbit Ig
Symbol
CALD1
NCBI Official Name
Caldesmon
NCBI Organism
Homo sapiens
Background Reference 01
Yoshio, T., FEBS Lett. 581 (20), 3777-3782 (2007) Mani, R.S., Biochemistry 31 (47), 11896-11901 (1992)
Other Product Names
Caldesmon, CDM, CALD1, CAD, CDM
Tested Applications
WB, IHC-P, Flow
Protein ID
338817891
Physical Properties
Liquid
Curated Selection
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