ABCC1 Antibody
Product Specifications
Background
ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC gene are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.
NCBI Gene ID
4363
Swiss Prot
P33527
Accession Number
P33527
Host
Rabbit
Reactivity
Human
Immunogen
This ABCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1247-1275 amino acids from the C-terminal region of human ABCC1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=62-353
Calculated Molecular Weight
172 kDa
Fragment
Rabbit Ig
Symbol
ABCC1
NCBI Official Name
Multidrug resistance-associated protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Siedlinski, M., Pharmacogenet. Genomics 19 (9), 675-684 (2009)
Other Product Names
Multidrug resistance-associated protein 1, ATP-binding cassette sub-family C member 1, Leukotriene C (4) transporter, LTC4 transporter, ABCC1, MRP, MRP1
Tested Applications
WB, Flow
Protein ID
296439301
Physical Properties
Liquid
Curated Selection
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