COL6A1 Antibody
Product Specifications
Background
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1 (VI), alpha2 (VI), and alpha3 (VI) chains. The protein COL6A1 is the alpha 1 subunit of type VI collagen (alpha1 (VI) chain) . Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.
NCBI Gene ID
1291
Swiss Prot
P12109
Accession Number
P12109
Host
Rabbit
Reactivity
Human
Immunogen
This COL6A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from the N-terminal region of human COL6A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=62-345
Calculated Molecular Weight
109 kDa
Fragment
Rabbit Ig
Symbol
COL6A1
NCBI Official Name
Collagen alpha-1 (VI) chain
NCBI Organism
Homo sapiens
Background Reference 01
Martoni, E., Hum. Mutat. 30 (5), E662-E672 (2009)
Background Reference 02
Kim, T.H., J. Rheumatol. 35 (9), 1849-1852 (2008)
Background Reference 03
Fujita, A., Genet. Mol. Res. (2), 371-378 (2008)
Other Product Names
Collagen alpha-1 (VI) chain, COL6A1
Tested Applications
WB, IHC-P, Flow
Protein ID
125987811
Physical Properties
Liquid
Curated Selection
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