C-fos Antibody
Product Specifications
Background
The Fos family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These leucine zipper proteins can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
NCBI Gene ID
2353
Swiss Prot
P01100
Accession Number
P01100
Host
Rabbit
Reactivity
Human
Immunogen
This c-fos antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-291 amino acids from the C-terminal region of human c-fos.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=62-343
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Symbol
FOS
NCBI Official Name
Proto-oncogene c-Fos
NCBI Organism
Homo sapiens
Background Reference 01
Gaggiotti, M.C., Biopolymers 91 (9), 710-718 (2009)
Other Product Names
Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7, FOS, G0S7
Tested Applications
WB, Flow
Protein ID
120470
Physical Properties
Liquid
Curated Selection
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