ARPC1A Antibody
Product Specifications
Background
ARPC1A is one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages.
NCBI Gene ID
10552
Swiss Prot
Q92747
Accession Number
Q92747
Host
Rabbit
Reactivity
Human
Immunogen
This ARPC1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-315 amino acids from the C-terminal region of human ARPC1A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
42 kDa
Fragment
Rabbit Ig
Symbol
ARPC1A
NCBI Official Name
Actin-related protein 2/3 complex subunit 1A
NCBI Organism
Homo sapiens
Background Reference 01
Laurila, E., Genes Chromosomes Cancer 48 (4), 330-339 (2009)
Background Reference 02
Machesky, L.M., Biochem. J. 328 (PT 1), 105-112 (1997)
Other Product Names
Actin-related protein 2/3 complex subunit 1A, SOP2-like protein, ARPC1A, SOP2L
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
88984001
Physical Properties
Liquid
Curated Selection
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