FIBB Antibody
Product Specifications
Background
FIBB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
NCBI Gene ID
2244
Swiss Prot
P02675
Accession Number
P02675
Host
Rabbit
Reactivity
Human
Immunogen
This FIBB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human FIBB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
56 kDa
Fragment
Rabbit Ig
Symbol
FGB
NCBI Official Name
Fibrinogen beta chain
NCBI Organism
Homo sapiens
Background Reference 01
Sun, A., Acta Cardiol 64 (3), 357-361 (2009)
Background Reference 02
Guo, X., Neurol. Res. 31 (4), 381-384 (2009)
Other Product Names
Fibrinogen beta chain, Fibrinopeptide B, Fibrinogen beta chain, FGB
Tested Applications
WB, IHC-P, Flow
Protein ID
399492
Physical Properties
Liquid
Curated Selection
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