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ATP7B Antibody

Product Specifications

Background

ATP7B is a member of the P-type cation transport ATPase family and a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile.

NCBI Gene ID

540

Swiss Prot

P35670

Accession Number

P35670

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ATP7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1361-1391 amino acids from the C-terminal region of human ATP7B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

157 kDa

Fragment

Rabbit Ig

Symbol

ATP7B

NCBI Official Name

Copper-transporting ATPase 2

NCBI Organism

Homo sapiens

Background Reference 01

Martinez-Balibrea, E., Int. J. Cancer 124 (12), 2905-2910 (2009)

Other Product Names

Copper-transporting ATPase 2, Copper pump 2, Wilson disease-associated protein, WND/140 kDa, ATP7B, PWD, WC1, WND

Tested Applications

WB, IHC-P, IF, Flow

Protein ID

239938919

Physical Properties

Liquid

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