ATP7B Antibody
Product Specifications
Background
ATP7B is a member of the P-type cation transport ATPase family and a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile.
NCBI Gene ID
540
Swiss Prot
P35670
Accession Number
P35670
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This ATP7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1361-1391 amino acids from the C-terminal region of human ATP7B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=62-284
Calculated Molecular Weight
157 kDa
Fragment
Rabbit Ig
Symbol
ATP7B
NCBI Official Name
Copper-transporting ATPase 2
NCBI Organism
Homo sapiens
Background Reference 01
Martinez-Balibrea, E., Int. J. Cancer 124 (12), 2905-2910 (2009)
Other Product Names
Copper-transporting ATPase 2, Copper pump 2, Wilson disease-associated protein, WND/140 kDa, ATP7B, PWD, WC1, WND
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
239938919
Physical Properties
Liquid
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