IL1RN Antibody
Product Specifications
Background
The protein is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. A polymorphism of its gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer.
NCBI Gene ID
3557
Swiss Prot
P18510
Accession Number
P18510
Host
Rabbit
Reactivity
Human
Immunogen
This IL1RN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-177 amino acids from the C-terminal region of human IL1RN.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=62-283
Calculated Molecular Weight
20 kDa
Fragment
Rabbit Ig
Symbol
IL1RN
NCBI Official Name
Interleukin-1 receptor antagonist protein
NCBI Organism
Homo sapiens
Background Reference 01
Kumar, S., Biochem. Biophys. Res. Commun. 387 (3), 456-460 (2009) Rechcinski, T., Kardiol Pol 67 (6), 601-610 (2009)
Other Product Names
Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, ICIL-1RA, IL1 inhibitor, Anakinra, IL1RN, IL1F3, IL1RA
Tested Applications
WB, IF, Flow
Protein ID
124312
Physical Properties
Liquid
Curated Selection
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