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IL1RN Antibody

Product Specifications

Background

The protein is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. A polymorphism of its gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer.

NCBI Gene ID

3557

Swiss Prot

P18510

Accession Number

P18510

Host

Rabbit

Reactivity

Human

Immunogen

This IL1RN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-129 amino acids from the Central region of human IL1RN.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

20 kDa

Fragment

Rabbit Ig

Symbol

IL1RN

NCBI Official Name

Interleukin-1 receptor antagonist protein

NCBI Organism

Homo sapiens

Background Reference 01

Kumar, S., Biochem. Biophys. Res. Commun. 387 (3), 456-460 (2009)

Background Reference 02

Rechcinski, T., Kardiol Pol 67 (6), 601-610 (2009)

Other Product Names

Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, ICIL-1RA, IL1 inhibitor, Anakinra, IL1RN, IL1F3, IL1RA

Tested Applications

WB, IHC-P, IF, Flow

Protein ID

124312

Physical Properties

Liquid

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