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Myosin 1C Antibody

Product Specifications

Background

MYO1C is a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane.

NCBI Gene ID

4641

Swiss Prot

O00159

Accession Number

O00159

Host

Rabbit

Reactivity

Human

Immunogen

This Myosin 1C (MYO1C) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 911-940 amino acids from the C-terminal region of human Myosin 1C (MYO1C) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

122 kDa

Fragment

Rabbit Ig

Symbol

MYO1C

NCBI Official Name

Unconventional myosin-Ic

NCBI Organism

Homo sapiens

Background Reference 01

Crozet F., Genomics 40:332-341 (1997) .

Other Product Names

Unconventional myosin-Ic, Myosin I beta, MMI-beta, MMIb, MYO1C

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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