RAD9 Antibody

Product Specifications

Background

Rad9 is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade.

NCBI Gene ID

5883

Swiss Prot

Q99638

Accession Number

Q99638

Host

Rabbit

Reactivity

Human

Immunogen

This RAD9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-279 amino acids from the Central region of human RAD9.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RAD9A

NCBI Official Name

Cell cycle checkpoint control protein RAD9A

NCBI Organism

Homo sapiens

Background Reference 01

Maniwa, Y., et al., Cancer 103 (1) :126-132 (2005) .

Background Reference 02

Wang, W., et al., Proc. Natl. Acad. Sci. U.S.A. 101 (48) :16762-16767 (2004) .

Background Reference 03

Lindsey-Boltz, L.A., et al., (er) Nucleic Acids Res. 32 (15) :4524-4530 (2004) .

Background Reference 04

Toueille, M., et al., (er) Nucleic Acids Res. 32 (11) :3316-3324 (2004) .

Other Product Names

Cell cycle checkpoint control protein RAD9A, hRAD9, DNA repair exonuclease rad9 homolog A, RAD9A

Tested Applications

Protein ID

74717382

Physical Properties

Liquid

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