Kallikrein 8 Antibody

Product Specifications

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. There are four different KLK8 isoforms, each exhibiting distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer.

NCBI Gene ID

11202

Swiss Prot

O60259

Accession Number

O60259

Host

Rabbit

Reactivity

Mouse

Immunogen

This Kallikrein 8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the Central region of human Kallikrein 8.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Symbol

KLK8

NCBI Official Name

Kallikrein-8

NCBI Organism

Homo sapiens

Background Reference 01

Li, Y., et al., Mol. Biol. Evol. 21 (11) :2111-2115 (2004) .

Background Reference 02

Shigemasa, K., et al., Oncol. Rep. 11 (6) :1153-1159 (2004) .

Background Reference 03

Cane, S., et al., Am. J. Obstet. Gynecol. 190 (1) :60-66 (2004) .

Background Reference 04

Clark, H.F., et al., Genome Res. 13 (10) :2265-2270 (2003) .

Other Product Names

Kallikrein-8, hK8, Neuropsin, NP, Ovasin, Serine protease 19, Serine protease TADG-14, Tumor-associated differentially expressed gene 14 protein, KLK8, NRPN, PRSS19, TADG14