Kallikrein 7 Antibody

Product Specifications

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK7 enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis.

NCBI Gene ID

5650

Swiss Prot

P49862

Accession Number

P49862

Host

Rabbit

Reactivity

Human

Immunogen

This Kallikrein 7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-187 amino acids from the C-terminal region of human Kallikrein 7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Symbol

KLK7

NCBI Official Name

Kallikrein-7

NCBI Organism

Homo sapiens

Background Reference 01

Planque, C., et al., Biochem. Biophys. Res. Commun. 329 (4) :1260-1266 (2005) .

Background Reference 02

Ishida-Yamamoto, A., et al., J. Invest. Dermatol. 124 (2) :360-366 (2005) .

Background Reference 03

Vasilopoulos, Y., et al., J. Invest. Dermatol. 123 (1) :62-66 (2004) .

Background Reference 04

Santin, A.D., et al., Gynecol. Oncol. 94 (2) :283-288 (2004) .

Other Product Names

Kallikrein-7, hK7, Serine protease 6, Stratum corneum chymotryptic enzyme, hSCCE, KLK7, PRSS6, SCCE

Tested Applications

WB, IHC-P, Flow

Protein ID

1710878

Physical Properties

Liquid

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