Kallikrein 6 Antibody

Product Specifications

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.

NCBI Gene ID

5653

Swiss Prot

Q92876

Accession Number

Q92876

Host

Rabbit

Reactivity

Human

Immunogen

This Kallikrein 6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-156 amino acids from the Central region of human Kallikrein 6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

27 kDa

Fragment

Rabbit Ig

Symbol

KLK6

NCBI Official Name

Kallikrein-6

NCBI Organism

Homo sapiens

Background Reference 01

Christophi, G.P., et al., J. Neurochem. 91 (6) :1439-1449 (2004) .

Background Reference 02

Bayes, A., et al., Biol. Chem. 385 (6) :517-524 (2004) .

Background Reference 03

Pampalakis, G., et al., Biochem. Biophys. Res. Commun. 320 (1) :54-61 (2004) .

Background Reference 04

Ghosh, M.C., et al., Tumour Biol. 25 (4) :193-199 (2004) .

Other Product Names

Kallikrein-6, 3421-, Neurosin, Protease M, SP59, Serine protease 18, Serine protease 9, Zyme, KLK6, PRSS18, PRSS9

Tested Applications

WB, IHC-P, Flow

Protein ID

3914480

Physical Properties

Liquid

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