Kallikrein 5 Antibody

Product Specifications

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK5 expression is up-regulated by estrogens and progestins. The protein is secreted and may be involved in desquamation in the epidermis.

NCBI Gene ID

25818

Swiss Prot

Q9Y337

Accession Number

Q9Y337

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Kallikrein 5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-174 amino acids from the Central region of human Kallikrein 5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

32 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

KLK5

NCBI Official Name

Kallikrein-5

NCBI Organism

Homo sapiens

Background Reference 01

Planque, C., et al., Biochem. Biophys. Res. Commun. 329 (4) :1260-1266 (2005) . Michael, I.P., et al., J. Biol. Chem. 280 (15) :14628-14635 (2005) . Ishida-Yamamoto, A., et al., J. Invest. Dermatol. 124 (2) :360-366 (2005) . Brattsand, M., et al., J. Invest. Dermatol. 124 (1) :198-203 (2005) . Caubet, C., et al., J. Invest. Dermatol. 122 (5) :1235-1244 (2004) .