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VEGFD Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C.

NCBI Gene ID

2277

Swiss Prot

O43915

Accession Number

O43915

Host

Rabbit

Reactivity

Human

Immunogen

This VEGFD (VEGF4) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-352 amino acids from the C-terminal region of human VEGFD (VEGF4) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

40 kDa

Fragment

Rabbit Ig

Symbol

FIGF

NCBI Official Name

Vascular endothelial growth factor D

NCBI Organism

Homo sapiens

Background Reference 01

Orlandini, M., et al., J. Biol. Chem. 278 (45) :44650-44656 (2003) .

Background Reference 02

McColl, B.K., et al., J. Exp. Med. 198 (6) :863-868 (2003) .

Background Reference 03

Rissanen, T.T., et al., Circ. Res. 92 (10) :1098-1106 (2003) .

Background Reference 04

Nakamura, Y., et al., Clin. Cancer Res. 9 (2) :716-721 (2003) .

Other Product Names

Vascular endothelial growth factor D, VEGF-D, c-Fos-induced growth factor, FIGF, FIGF, VEGFD

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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