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ELK1 Antibody

Product Specifications

Background

ELK1 is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein is a nuclear target for the ras-raf-MAPK signaling cascade.

NCBI Gene ID

2002

Swiss Prot

P19419

Accession Number

P19419

Host

Rabbit

Reactivity

Human

Immunogen

This ELK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 361-390 amino acids from human ELK1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ELK1

NCBI Official Name

ETS domain-containing protein Elk-1

NCBI Organism

Homo sapiens

Background Reference 01

Salinas, S., et al., J. Cell Biol. 165 (6) :767-773 (2004) .

Background Reference 02

Yang, S.H., et al., Mol. Cell 12 (1) :63-74 (2003) .

Background Reference 03

Bebien, M., et al., Oncogene 22 (12) :1836-1847 (2003) .

Background Reference 04

Sharrocks, A.D., Biochem. Soc. Trans. 30 (2) :1-9 (2002) .

Other Product Names

ETS domain-containing protein Elk-1, ELK1

Tested Applications

WB

Protein ID

12643407

Physical Properties

Liquid

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