HSC70 Interacting Protein HIP Antibody

Product Specifications

Background

ST13 is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this protein is reported to be downregulated in colorectal carcinoma tissue suggesting that is a candidate tumor suppressor.

NCBI Gene ID

6767

Swiss Prot

P50502

Accession Number

P50502

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This HSC70 Interacting Protein HIP (ST13) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-80 amino acids from human HSC70 Interacting Protein HIP (ST13) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

41 kDa

Fragment

Rabbit Ig

Symbol

ST13

NCBI Official Name

Hsc70-interacting protein

NCBI Organism

Homo sapiens

Background Reference 01

Rajapandi, T., et al., J. Biol. Chem. 275 (29) :22597-22604 (2000) .

Background Reference 02

Morishima, Y., et al., J. Biol. Chem. 275 (10) :6894-6900 (2000) .

Background Reference 03

Chen, S., et al., J. Biol. Chem. 273 (52) :35194-35200 (1998) .

Background Reference 04

Johnson, B.D., et al., J. Biol. Chem. 273 (6) :3679-3686 (1998) .

Other Product Names

Hsc70-interacting protein, Hip, Aging-associated protein 2, Progesterone receptor-associated p48 protein, Protein FAM10A1, Putative tumor suppressor ST13, Renal carcinoma antigen NY-REN-33, Suppression of tumorigenicity 13 protein, ST13, AAG2, FAM10A1, HIP, SNC6