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MMP20 Antibody

Product Specifications

Background

MMP20 degrades amelogenin, the major protein component of the enamel matrix, as well as two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP) . MMP20 may play a central role in tooth enamel formation.

NCBI Gene ID

9313

Swiss Prot

O60882

Accession Number

O60882

Host

Rabbit

Reactivity

Human

Immunogen

This MMP20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 233-262 amino acids from the Central region of human MMP20.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Symbol

MMP20

NCBI Official Name

Matrix metalloproteinase-20

NCBI Organism

Homo sapiens

Background Reference 01

Llano, E., et al., Biochemistry 36 (49) :15101-15108 (1997) .

Background Reference 02

Stracke, J.O., et al., FEBS Lett. 478 (1-2), 52-56 (2000) .

Other Product Names

Matrix metalloproteinase-20, MMP-20, 3424-, Enamel metalloproteinase, Enamelysin, MMP20

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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