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MMP19 Antibody

Product Specifications

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The function of MMP19 has not been determined. This gene was previously referred to as MMP18 but has been renamed matrix metalloproteinase 19 (MMP19) .

NCBI Gene ID

4327

Swiss Prot

Q99542

Accession Number

Q99542

Host

Rabbit

Reactivity

Human

Immunogen

This MMP19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human MMP19.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=62-175

Calculated Molecular Weight

57 kDa

Fragment

Rabbit Ig

Symbol

MMP19

NCBI Official Name

Matrix metalloproteinase-19

NCBI Organism

Homo sapiens

Background Reference 01

Sadowski, T., et al., Mol. Biol. Cell 14 (11) :4569-4580 (2003) .

Background Reference 02

Impola, U., et al., Int. J. Cancer 103 (6) :709-716 (2003) .

Background Reference 03

Mauch, S., et al., J. Immunol. 168 (3) :1244-1251 (2002) .

Background Reference 04

Stracke, J.O., et al., J. Biol. Chem. 275 (20) :14809-14816 (2000) .

Other Product Names

Matrix metalloproteinase-19, MMP-19, 3424-, Matrix metalloproteinase RASI, Matrix metalloproteinase-18, MMP-18, MMP19, MMP18, RASI

Tested Applications

WB, IHC-P, Flow

Protein ID

12643345

Physical Properties

Liquid

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