What is the catalog number for MMP16 Antibody?

The catalog number for MMP16 Antibody is 62-173.

What sizes are available for MMP16 Antibody?

MMP16 Antibody is available in the following size(s): 400 µL.

Is MMP16 Antibody in stock?

MMP16 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

MMP16 Antibody

Product Specifications

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene for MMP16 produces two transcripts, which encode a membrane-bound form and a soluble form of the protein. Both forms of the protein activate MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.

NCBI Gene ID

4325

Swiss Prot

P51512

Accession Number

P51512

Host

Rabbit

Reactivity

Human

Immunogen

This MMP16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the N-terminal region of human MMP16.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

70 kDa

Fragment

Rabbit Ig

Symbol

MMP16

NCBI Official Name

Matrix metalloproteinase-16

NCBI Organism

Homo sapiens

Background Reference 01

Jung, M., et al., Prostate 55 (2) :89-98 (2003) .

Background Reference 02

Nagase, H., et al., J. Biol. Chem. 274 (31) :21491-21494 (1999) .

Background Reference 03

Matsumoto, S., et al., Biochim. Biophys. Acta 1354 (2) :159-170 (1997) .

Background Reference 04

Sato, H., et al., Genomics 39 (3) :412-413 (1997) .

Other Product Names

Matrix metalloproteinase-16, MMP-16, 3424-, MMP-X2, Membrane-type matrix metalloproteinase 3, MT-MMP 3, MTMMP3, Membrane-type-3 matrix metalloproteinase, MT3-MMP, MT3MMP, MMP16, MMPX2