MMP10 Antibody
Product Specifications
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP10 degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
NCBI Gene ID
4319
Swiss Prot
P09238
Accession Number
P09238
Host
Rabbit
Reactivity
Human
Immunogen
This MMP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-423 amino acids from the C-terminal region of human MMP10.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
54 kDa
Fragment
Rabbit Ig
Symbol
MMP10
NCBI Official Name
Stromelysin-2
NCBI Organism
Homo sapiens
Background Reference 01
Nagase, H., et al., J. Biol. Chem. 274 (31) :21491-21494 (1999) .
Background Reference 02
Pendas, A.M., et al., Genomics 37 (2) :266-268 (1996) .
Background Reference 03
Jung, J.Y., et al., Ann. Genet. 33 (1) :21-23 (1990) .
Background Reference 04
Sirum, K.L., et al., Biochemistry 28 (22) :8691-8698 (1989) .
Other Product Names
Stromelysin-2, SL-2, Matrix metalloproteinase-10, MMP-10, Transin-2, MMP10, STMY2
Tested Applications
WB, IHC-P
Protein ID
116869
Physical Properties
Liquid
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