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MAGEC1 Antibody

Product Specifications

Background

MAGEC1 is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, thus is about 800 residues longer than the other MAGE proteins. This gene is expressed in a significant proportion of tumors of various histological types, whereas it is silent in normal tissues, except testis. The function of this gene is unknown.

NCBI Gene ID

9947

Swiss Prot

O60732

Accession Number

O60732

Host

Rabbit

Reactivity

Human

Immunogen

This MAGEC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 849-880 amino acids from the C-terminal region of human MAGEC1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=62-156

Calculated Molecular Weight

124 kDa

Fragment

Rabbit Ig

Symbol

MAGEC1

NCBI Official Name

Melanoma-associated antigen C1

NCBI Organism

Homo sapiens

Background Reference 01

Jungbluth, A.A., et al., Int. J. Cancer 99 (6) :839-845 (2002) .

Background Reference 02

Chen, Y.T., et al., Proc. Natl. Acad. Sci. U.S.A. 95 (12) :6919-6923 (1998) .

Background Reference 03

Lucas, S., et al., Cancer Res. 58 (4) :743-752 (1998) .

Background Reference 04

Lim, S.H., et al., Eur. J. Haematol. 67 (5-6), 332-334 (2001) .

Other Product Names

Melanoma-associated antigen C1, Cancer/testis antigen 71, CT71, MAGE-C1 antigen, MAGEC1

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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