MAGEC1 Antibody
Product Specifications
Background
MAGEC1 is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, thus is about 800 residues longer than the other MAGE proteins. This gene is expressed in a significant proportion of tumors of various histological types, whereas it is silent in normal tissues, except testis. The function of this gene is unknown.
NCBI Gene ID
9947
Swiss Prot
O60732
Accession Number
O60732
Host
Rabbit
Reactivity
Human
Immunogen
This MAGEC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 849-880 amino acids from the C-terminal region of human MAGEC1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
124 kDa
Fragment
Rabbit Ig
Symbol
MAGEC1
NCBI Official Name
Melanoma-associated antigen C1
NCBI Organism
Homo sapiens
Background Reference 01
Jungbluth, A.A., et al., Int. J. Cancer 99 (6) :839-845 (2002) .
Background Reference 02
Chen, Y.T., et al., Proc. Natl. Acad. Sci. U.S.A. 95 (12) :6919-6923 (1998) .
Background Reference 03
Lucas, S., et al., Cancer Res. 58 (4) :743-752 (1998) .
Background Reference 04
Lim, S.H., et al., Eur. J. Haematol. 67 (5-6), 332-334 (2001) .
Other Product Names
Melanoma-associated antigen C1, Cancer/testis antigen 71, CT71, MAGE-C1 antigen, MAGEC1
Tested Applications
WB, IHC-P
Physical Properties
Liquid
Frequently Asked Questions
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