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Leptin Antibody

Product Specifications

Background

Leptin (LEP) is an adipocyte-secreted protein that regulates body fat and endocrine functions. Leptin is similar to the mouse obesity protein encoded by the obese gene (ob) . In mouse studies, mutations in this gene are linked to severe and morbid obesity.

NCBI Gene ID

3952

Swiss Prot

P41159

Accession Number

P41159

Host

Rabbit

Reactivity

Human

Immunogen

This Leptin (LEP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-166 amino acids from the C-terminal region of human Leptin (LEP) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

19 kDa

Fragment

Rabbit Ig

Symbol

LEP

NCBI Official Name

Leptin

NCBI Organism

Homo sapiens

Background Reference 01

Tank, J., et al., J. Clin. Endocrinol. Metab. 88 (10) :4955-4959 (2003) .

Background Reference 02

Silha, J.V., et al., Eur. J. Endocrinol. 149 (4) :331-335 (2003) .

Background Reference 03

Kazumi, T., et al., Metab. Clin. Exp. 52 (9) :1113-1116 (2003) .

Background Reference 04

Mullington, J.M., et al., J. Neuroendocrinol. 15 (9) :851-854 (2003) .

Other Product Names

Leptin, Obese protein, Obesity factor, LEP, OB, OBS

Tested Applications

WB, IF

Physical Properties

Liquid

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