Jagged 2 Antibody
Product Specifications
Background
The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. JAG2 is one of several ligands that activate Notch and related receptors.
NCBI Gene ID
3714
Swiss Prot
Q9Y219
Accession Number
Q9Y219
Host
Rabbit
Reactivity
Human
Immunogen
This Jagged 2 (JAG2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1209-1238 amino acids from the C-terminal region of human Jagged 2 (JAG2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
133 kDa
Fragment
Rabbit Ig
Symbol
JAG2
NCBI Official Name
Protein jagged-2
NCBI Organism
Homo sapiens
Background Reference 01
Hayashi, T., et al., J. Androl. 22 (6) :999-1011 (2001) .
Background Reference 02
Lindner, V., et al., Am. J. Pathol. 159 (3) :875-883 (2001) .
Background Reference 03
Cereseto, A., et al., J. Cell. Physiol. 185 (3) :425-431 (2000) .
Background Reference 04
Tsai, S., et al., Blood 96 (3) :950-957 (2000) .
Other Product Names
Protein jagged-2, Jagged2, hJ2, JAG2
Tested Applications
WB, IHC-P
Protein ID
116242598
Physical Properties
Liquid
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