EDG2 Antibody

Product Specifications

Background

The EDG2 integral membrane protein is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion.

NCBI Gene ID

1902

Swiss Prot

Q92633

Accession Number

Q92633

Host

Rabbit

Reactivity

Human

Immunogen

This EDG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human EDG2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction, Growth Factors

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

41 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

LPAR1

NCBI Official Name

Lysophosphatidic acid receptor 1

NCBI Organism

Homo sapiens

Background Reference 01

Matsuda, A., et al., Oncogene 22 (21) :3307-3318 (2003) .

Background Reference 02

Van Leeuwen, F.N., et al., J. Biol. Chem. 278 (1) :400-406 (2003) .

Background Reference 03

Shida, D., et al., Cancer Res. 63 (7) :1706-1711 (2003) .

Background Reference 04

Cervera, P., et al., Glia 38 (2) :126-136 (2002) .

Other Product Names

Lysophosphatidic acid receptor 1, LPA receptor 1, LPA-1, Lysophosphatidic acid receptor Edg-2, LPAR1, EDG2, LPA1

Tested Applications

Protein ID

26454626

Physical Properties

Liquid

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